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Botanical Medicine Posts (BMP)

Since December 24, 2008
Showing posts with label Drugs. Show all posts
Showing posts with label Drugs. Show all posts

Sunday, November 14, 2010

Who Pays for Drug Review Done by the FDA?

In the United States, the Food and Drug Administration (FDA) is charged in approving pharmaceutical products to be placed on the market. The main two components of this FDA approval are the Safety and Efficacy of the product. There is no such chemical that does not cause side effects if taken internally. However, the FDA considers in its approval process a balance between these two factors. A drug with a poor safety profile would never reach the market despite its efficacy. Or would it? Drugs are routinely removed from the market by the FDA for safety reasons. In fact, more than 6,500 pharmaceutical products are pulled out the pharmacy shelves since 1975! The process of FDA approval is tedious and requires experts panels to make a "recommendation" whether a pharmaceutical product should be available to the public. The decision is not always a straight forward one, and oftentimes the line between approval and denial is blurred. Surveys have revealed that "experts" sitting on these FDA panels oftentimes have ties to the pharmaceutical industry, and even ties to the same company its product is under review. Moreover, the Congress has passed laws to require that the cost of pharmaceutical products' review be paid, in part, by the pharmaceutical company sponsoring the submission. The FDA is being paid by the same sponsor to review the sponsor's product?! The Congress had good intention to shift the burden of cost from the taxpayer to the pharmaceutical industry, however by doing so has created a "conflict of interest". I propose a solution to this dilemma. Perhaps we can keep the burden of cost for review on the pharmaceutical industry, however the FDA will hire a private agency to submit the recommendation to it for approval. The private agency will be paid by the FDA, and decisions on the product rest solely with the private agency. As a requirement, the private agency's employees must have no ties with the pharmaceutical industry. And, for the FDA to over rule the recommendations of the private agency, the FDA has to come up with scientifically good reasons reviewed and approved by the Institute of Medicine. The system as it is now does not protect the consumer from "bad drugs". The recent cases with the COX-2 inhibitor drugs (anti-inflammatory agents) and their dangerous side effects on the heart muscle beg the question: Who is really watching out for us when it comes to drug safety?

Monday, November 8, 2010

Physicians and Medicines

It is no secret that many physicians in the United States learn about the use of drugs from drug representatives. Oftentimes, the drug representatives bring with them free drug samples, and many physicians accept these for distribution to their patients. The doctors justify the acceptance of samples by stating that these will help patients who cannot afford the medicines. However, studies have shown that this justification is not true, and the majority of drug samples go to wealthy people with medical insurance. Drug companies are in the business of giving money and gifts to physicians, and unfortunately this would eventually reflect on their prescription pattern. Next time you visit your doctor ask him/her if they receive any money or gifts from pharmaceutical companies. If the answer is affirmative, then just leave the office. If all of us do that, the physicians eventually get it. Physicians live in an alternate world; it is time that we brought them back to planet Earth.

Saturday, June 5, 2010

How Many Arab Countries are There?

There are 22 Arab countries. These are (not in alphabetic order): Lebanon, Syria, Jordan, Egypt, Iraq, Libya, Tunisia, Morocco, Sudan, Djibouti, Yemen, Kingdom of Saudi Arabia, Oman, United Arab Emirates, Mauritania, Comoros, Algeria, Kuwait, Qatar, Somalia, Bahrain, and Palestine.

One interesting fact among all these nations that is rarely known is that: if you were a citizen of one of those countries you do not need a visa to cross any of these countries' borders. You just need a passport. Imagine if this would happen one day among the citizens of the American Continent. I am allowed to imagine it, am I not? Imagine that one day there is no need for laws similar to "illegal aliens" law in Arizona. Imagine if that happens, the human smuggling business would be gone. The only people who would want to cross the border "illegally" are drug smugglers, which we need harsher laws for them than we have today to stop their filthy deeds. By the way, drug traffickers in many of the Arab World meet their destiny by hanging, and withing few days from the day they are caught. Because of that, illegal drug use in the Arab World is either unheard of or if it exists, is not significant (some illegal drugs escape from Turkey into the Arab World).

Sunday, October 4, 2009

Direct-to-Consumer Ads Should be Banned

Since the US FDA has relaxed its rules governing drug advertisements, the amount of money spent on these ads by the pharmaceutical companies has increased tremendously. Of course, the results are patients "demanding" a specific treatment from their doctors. Every time I listen to the side effects, that are usually said just before another "benign" final statement, make my stomach turns. Can you imagine how gullible the people are? Just some pretty faces, well-known actors, or some seemingly "everyday people" making the pitch for the drug does not mean everybody needs these drugs. Even physicians fall prey to these ads, after all they watch TV too! Just get rid of them; the public does not want them.

Tuesday, September 8, 2009

Cautions and Warnings

1) Botanicals or herbals must never be taken by the following people (unless it is recommended by their physicians): the very young (under 12 years), pregnant women, and nursing mothers. This is a general precaution.

2) Always communicate with your physician concerning any herbal treatment that you are currently taking.

3) Never take any herbal product if you are on prescription or over-the-counter medications.

4) Drug/herb or herb/herb interactions do occur, and consequences could be severe, and even death may occur.

Saturday, April 25, 2009

What's Wrong with Compounding Pharmacy?


The answer is simply "nothing is wrong". The recent horse killing by a compounded prescription has raised the awareness that drugs when compounded irresponsibly could kill. But this is nothing new about drugs and medicine. Every year our health care system kills over 100,000 people, a well known, but unbelievable fact. And compounding pharmacy is a small contributor to this epidemic. Although these were beautiful expensive horses, it was good that these were not people who got killed. Perhaps this is a good message to all pharmacists, check your weighing twice and ask someone else to check it for you. Saving lives is worse a few extra minutes from your time.

Sunday, March 15, 2009

Multimodal Anesthesia

The field of multimodal anesthesia has few stars, among them was Dr. Scott Reuben from Massachusetts. TheScientist.com reported that Dr. Reuben had falsified over 21 reports dealing with this same subject, including "making up entire studies". His collaboration with Pfizer on many research studies begged the question whether he also had falsified results in those studies as well. Experts in this field doubt that Pfizer's results were tainted citing "the level of auditing is just too intense" by the company to be able to fake results, according to TheScientist.com.

Saturday, March 14, 2009

Why Medicines Don't Always Work?

Most new drugs on the market are tooted as the best solution ever for a given disease. Once the "new drugs" become old, their "effectiveness" somewhat diminishes. This is because most, if not, all drugs carry with them a placebo effect. A quick look in the PDR (Physician Desk Reference) reveals that for some drugs the placebo effect may be as high as 50%! So, what is the secret behind this mysterious healing power that Traditional Western Medicine advocate for? Most doctors would not tell you that 80% of diseases heal on their own. That leaves us with 20% of disease states that may require some intervention. About 1/3 of the 20% disease states, the Traditional Western Medicine are clueless about. If you hear the word "Idiopathic", this means the Traditional Western Medicine have no clue what causes it, but yet they go and prescribe something to "treat" it. They even use the word Idiopathic to impress uneducated patients. Most of the diseases in the 20% category are related to cancer, cardiovascular illnesses, and other degenerative diseases. Traditional Western Medicine combats those with "burning, poisoning, or cutting" methods that often are unnecessary or at best limited in their effectiveness. Most illnesses the GP sees in a given day can be treated with a handful of drugs: the antibiotics, the anti-inflammatory, the anti-depressives, and the likes. Traditional Western Medicine cannot provide adequate disease management anymore. The cost is simply too high for such ineffective and limited treatments.

Monday, February 23, 2009

Tarragon

Tarragon is an herb originated in Russia. The French use it in their fine cuisine to enhance the flavor of foods. Many Middleastern cooking depends on Tarragon as an appetizer and flavor enhancer, especially with rice served with vegetables and lamb. Some use it with backed lamb patties (Kibeh). Tarragon is an excellent source for iodine. Some people suggest the use of its roots to calm a toothache. Chewing Tarragon leaves can result in a slight numbness of taste buds. This characteristic can be used to "mask" the taste of unpleasant drugs. Tarragon also contains a significant amount of vitamins A and C. Although Tarragon is not as popular in the United States as it is in Europe, it is usually found among Middleasterners and Europeans communities in the US. For those who get frequent indigestion when eating, Tarragon can be an excellent herb to help digestion.

Sunday, February 22, 2009

Dietary Supplements vs. Drugs

In the United States, the FDA is charged with "licensing" drugs. This process is extremely vigorous and normally takes many years to be fully completed. Millions of dollars are normally spent for an agent to become a drug . For that, the agent should be tested for its safety and effectiveness. To that end, numerous tests are performed in test tubes, in cell culture, and in vivo (both on animals and human) to "prove" that the drug is effective for the condition being marketed for, and it is safe to use. When it comes to dietary supplements the assumption for effectiveness is not required, and it is up to the FDA to prove that a dietary supplement already available on the market to be dangerous to the public. It is a line from "Alice in Wonderland" story. All dietary supplements, without exception, cannot and should not be deemed effective for any malady, unless the FDA says so. Also, the public should be very wary about these products safety. No standardized measures have been taken so far by the government to assure the consumer the "safety" of these products. However, it is reasonable to suggest that if the FDA has not yet taken an official action on a particular product, that product "may" be safe. Consumers should not think that these dietary supplements are drugs, and should not use them as such. The FDA was put in place to protect the public, and it is doing a wonderful job at it.

Thursday, January 29, 2009

Why do my pills cost $3 each?

The cost of most pharmaceuticals is not in the actual "materials" being used in making the tablets or capsules. The cost is in the invention. It takes professionals to discover new drugs, test them for their effects, and prepare them into tablets and capsules. In addition, only a tiny fraction of new chemicals or agents ever make it to the market. (It is estimated that only one out of 20,000 new agents tested ever make it to the market.) Most manufacturers recycle a portion of their profit in Research & Development (R&D). R&D produces new drugs to cure diseases. Is this worth $3/pill?

Friday, January 23, 2009

What percentage of our current western medicines is natural?

It is estimated that about 50% of all the drugs on the market have natural origin. About 25% of them are from plants and the other 25% are derivatives of components in plants.

Sunday, January 18, 2009

Antioxidants and Chemotherapy

Drugs used to treat cancer (chemotherapy) may become partially or fully infective if taken with antioxidants. The reason is that some chemotherapeutic drugs' action is through free radicals formation. Antioxidants scenvage free radicals, thus reducing the effectiveness of these drugs.

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The Ten Commandments

EXODUS 20:1-17 (The Orthodox Study Bible)


"Now the Lord spoke all these words, saying;


I am the Lord your God, who brought you out of the land of Egypt, out of the house of bondage. You shall have no other gods before Me.


You shall not make for yourself an idol or a likeness of anything in heaven above, or in the earth beneath, or in the waters under the earth. You shall not bow down to them, for I, the Lord your God, am a jealous God, recompensing the sins of the fathers on the children to the third and fourth generation of those who hate Me; but showing mercy to thousands, to those who love Me and keep My commandments.


You shall not take the name of the Lord your God in vain, for the Lord will not hold him guiltless who takes His name in vain.


Remember the Sabbath Day, to keep it holy. Six days you shall labor and do all your work, but the seventh day is the Sabbath of the Lord your God. In it you shall do no work: neither you, nor your son, your daughter, your male servant, your female servant, your cattle, nor your stranger who sojourns with you. For in six days the Lord made heaven and earth, the sea, and everything in them, and rested on the seventh day. Therefore, the Lord blessed the Sabbath Day and hallowed it.


Honor your father and mother that it may be well with you, and your days may be long upon the good land the Lord your God is giving you.


You shall not murder.


You shall not commit adultery.


You shall not steal.


You shall not bear false witness against your neighbor.


You shall not covet your neighbor's wife or his house, and neither shall you covet his field, nor his male servant, his female servant, his ox, his donkey, any of his cattle, or whatever belongs to your neighbor."

Bible Dates (The Orthodox Study Bible)

Genesis (Moses) (During Israel's forty years of wandering in the wilderness-the period between crossing the Red Sea and the entrance into Canaan)

Exodus (Moses) (During Israel's forty years of wandering in the wilderness-the period between crossing the Red Sea and the entrance into Canaan)

Leviticus (Moses) (The period during the sojourn at Mt. Sinai)

Numbers (Moses) (Following the exodus from Egypt)

Deuteronomy (Moses) (Near the end of Moses' life and before the entrance into Canaan)

Joshua (Joshua) (600 BC)

The Book of Judges (Samuel) (Three centuries after Israel entered Canaan and covers the period of these centuries)

Ruth (Unknown) (1300 BC)

The First Book of the Kingdoms (Samuel) (1070-970 BC)

The Second Book of the Kingdoms (Samuel) (971-890 BC)

The Third Book of the Kingdoms (Jeremiah) (600-550 BC)

The Fourth Book of the Kingdoms (Jeremiah and Others) (651-609)

The First Book of the Chronicles (Ezra) (450 BC)

The Second Book of the Chronicles (Ezra) ( 450 BC)

The First Book of Ezra (Uncertain) (150 BC)

The Second Book of Ezra (Ezra) (538-410 BC)

The Book of Nehemiah (Nehemiah) (445-425 BC)

The Book of Tobit (Unknown) (400-200 BC)

The Book of Judith (Unknown) (135-105 BC)

The Book of Esther (Mordecai) (450 BC)

The First Book of the Maccabees (Unknown) (104 BC)

The Second Book of the Maccabees (Unknown) (124 BC)

The Book of Psalms (David) (1000-several centuries thereafter)

The Book of Job (Unknown) (1600 BC)

The Proverbs (Solomon) (970-931 BC)

The Book of Ecclesiastes (Solomon) (935 BC)

The Song of Songs (Solomon) (965-960 BC)

The Wisdom of Solomon (Unknown) (30-10 BC)

The Wisdom of Sirach (Jesus of Sirach) (180 BC)

The Book of Hosea (Hosea) (750 BC)

The Book of Amos (Amos) (754 BC)

The Book of Micah (Micah) (Before 720 BC)

The Book of Joel (Joel) (740 BC)

The Book of Obadiah (Obadiah) (587 BC)

The Book of Jonah (Jonah) (784-772 BC)

The Book of Nahum (Nahum) (663-612 BC)

The Book of Habakkuk (Habakkuk) (605 BC)

The Book of Zephaniah (Zephaniah) (627-625 BC)

The Book of Haggai (520 BC)

The Book of Zachariah (Zechariah) (520-480 BC)

The Book of Malachi (Malachi) (500-350 BC)

The Book of Isaiah (Isaiah) (745-680 BC)

The Book of Jeremiah (Jeremiah) (627-582 BC)

The Book of Baruch (Baruch) (After 586 BC)

The Lamentation of Jeremiah (Jeremiah) (October 587-December 587 BC)

The Epistle of Jeremiah (Jeremiah) (597 BC-Exile to Babylon)

The Book of Ezekiel (Ezekiel) (595-572 BC)

The Book of Daniel (Daniel) (605-530 BC)

The Book of Matthew (Matthew) (50-70 AD)

The Book of Mark (Mark) (70 AD)

The Book of Luke (Luke) (70-80 AD)

The Book of John (John) (96 AD)

The Book of Acts (Luke) (75-85 AD)

The Book of Romans (St. Paul) (55-57 AD)

The First Book of the Corinthians (St. Paul) (55 AD)

The Second Book of the Corinthians (St. Paul) (55 AD)

The Book of Galatians (St. Paul) (Uncertain)

The Book of Ephesians (St. Paul) (61-63 AD)

The Book of Philippians (St. Paul) (61-63 AD)

The Book of Colossians (St. Paul) (61-63 AD)

The First Book of Thessalonians (St. Paul) (50-51 AD)

The Second Book of Thessalonians (St. Paul) (51 AD)

The First Book of Timothy (St. Paul) (64-65 AD)

The Second Book of Timothy (St. Paul) (65-67 AD)

The Book of Titus (St. Paul) (63-65 AD)

The Book of Philemon (St. Paul) (61-63 AD)

The Book of Hebrews (St. Paul) (70 AD)

The Book of James (James) (55-60 AD)

The First Book of Peter (Peter) (50-67 AD)

The Second Book of Peter (Peter) (63-67 AD)

The First Book of John (John) (90-95 AD)

The Second Book of John (John) (90-95 AD)

The Third Book of John (John) (90-95 AD)

The Book of Jude (Jude) (60-80 AD)

The Book of the Revelation (John) (81-96 AD)

Rocks of Mars (NASA)

 

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Martians 15

Martians 15
A Face of A Martian (NASA Images)

Martians (5)

Martians (5)
A Martian Lion (NASA Images)

Martians (6)

Martians (6)
Figures of Martians Printed on Sands (Mars/Sol 1207/NASA Images)

Martians (7)

Martians (7)
A Dino Imprint on Sands on Planet Mars (NASA Images/Sol 1207)

Martians (8)

Martians (8)
Santa Clause is Coming to (Martian) Town (NASA Images)

Martians (9)

Martians (9)
Martian Sandman (Ignor the rocks and focus on the sands) (NASA Images)

Martians (10)

Martians (10)
A Hologram of a Man (Martian) in Sands (NASA Images)

Martian (11)

Martian (11)
Martian Figures Printed on Sand (NASA Images)

Martians (14)

Martians (14)
NASA Images: Imprints on Martian Rocks

Martians (12)

Martians (12)
A little Martian guy printed in sand (NASA Images)

Martians 13

Martians 13
A head statue found on Mars (NASA Images)
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Northeastern University Alumnus

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